IGF-1 LR3 1mg
As low as A$144.00/unit
Research Use Only: This product is sold for laboratory and in-vitro research purposes. Not for human consumption or therapeutic use.
Product Details
Health Benefits of IGF-1 LR3 1mg
Extended Half-Life IGF-1 Analogue
IGF-1 LR3 (Long R3 IGF-1) is a modified version of insulin-like growth factor 1 with a glutamic acid-to-arginine substitution at position 3 and a 13-amino-acid N-terminal extension. These modifications reduce binding to IGF-binding proteins (IGFBPs), extending its half-life from ~15 minutes to ~20-30 hours.
Potent Anabolic Research Compound
IGF-1 LR3 has approximately 2-3x greater biological potency than native IGF-1 due to its reduced IGFBP binding. This enhanced bioavailability makes it a powerful tool for studying IGF-1 receptor signalling and its downstream anabolic effects.
Muscle Hypertrophy Research
Research demonstrates IGF-1 LR3 promotes skeletal muscle hypertrophy through satellite cell activation, myoblast proliferation, and enhanced protein synthesis. It activates the PI3K/Akt/mTOR signalling cascade — the primary pathway for muscle growth.
Cell Proliferation & Differentiation
IGF-1 LR3 is widely used in cell culture research to promote cell growth, proliferation, and differentiation. It supports the growth of various cell types and is a common supplement in serum-free cell culture media.
Anti-Apoptotic Effects
Research shows IGF-1 signalling through the PI3K/Akt pathway promotes cell survival by inhibiting apoptosis (programmed cell death). IGF-1 LR3's enhanced potency makes it valuable for studying these cytoprotective mechanisms.
Metabolic Research Applications
IGF-1 plays key roles in glucose metabolism, lipid metabolism, and insulin sensitivity. IGF-1 LR3's extended activity allows researchers to study these metabolic effects over longer timeframes than native IGF-1.
Note: The health benefits listed above are based on published scientific research and clinical studies. Individual results may vary. This product is sold for research purposes only — not for human consumption. Always consult published literature for detailed study methodologies and findings.
Frequently Asked Questions — IGF-1 LR3 1mg
What is IGF-1 LR3?
IGF-1 LR3 (Long R3 Insulin-like Growth Factor 1) is a synthetic analogue of human IGF-1. It has two key modifications: a glutamic acid-to-arginine substitution at position 3 (hence 'R3') and a 13-amino-acid N-terminal extension peptide. These changes dramatically reduce binding to IGF-binding proteins, increasing its bioavailability and extending its half-life to 20-30 hours.
How does IGF-1 LR3 differ from native IGF-1?
Native IGF-1 has a short half-life (~15 minutes) because it is rapidly bound by IGF-binding proteins (IGFBPs). IGF-1 LR3's modifications reduce IGFBP binding by >95%, resulting in 2-3x greater potency and a half-life of 20-30 hours. This makes it significantly more practical for research applications.
What is the role of IGF-1 in the GH/IGF axis?
IGF-1 is the primary mediator of growth hormone's anabolic effects. GH stimulates IGF-1 production primarily in the liver, and IGF-1 then acts on target tissues to promote cell growth, protein synthesis, and metabolic effects. IGF-1 also provides negative feedback to the pituitary, regulating GH secretion.
Can I buy IGF-1 LR3 in Australia?
Yes — OzTideLab ships IGF-1 LR3 1mg across Australia via Australia Post. Free standard shipping on orders over A$199. HPLC-verified ≥98% purity, discreet packaging, and PayID/Osko payment accepted.
Research Applications
This peptide is supplied for in-vitro laboratory research only. Common research applications include receptor binding assays, cell culture studies, structure-activity relationship analysis, and bioassay development. Researchers should consult relevant literature for specific experimental protocols.
Storage & Handling
- • Store lyophilised powder at -20°C for long-term stability
- • Short-term storage: 2-8°C (refrigerated)
- • Protect from light, moisture, and repeated freeze-thaw cycles
- • Once reconstituted, use within the recommended timeframe
Purity & HPLC Analysis
Every batch is independently verified via High-Performance Liquid Chromatography (HPLC) to confirm ≥98% purity. Mass spectrometry (MS) is used for molecular identity confirmation. Certificates of Analysis (CoA) are available on request — email support@oztidelab.com with your order number.
Reconstitution Guidelines
- • Use bacteriostatic water or sterile water for reconstitution
- • Add solvent slowly along the vial wall — do not shake
- • Gently swirl until fully dissolved (clear solution)
- • Store reconstituted solution at 2-8°C and use within 28 days
- • Use sterile technique throughout to prevent contamination
HPLC Verified
≥98% purity certified
Australian Owned
Local team, local support
Discreet Shipping
Plain packaging AU-wide
Research Grade
Lab-quality peptides
