IGF-DES 2mg
As low as A$144.00/unit
Research Use Only: This product is sold for laboratory and in-vitro research purposes. Not for human consumption or therapeutic use.
Product Details
Health Benefits of IGF-DES 2mg
Highest Potency IGF-1 Variant
IGF-DES (Des(1-3) IGF-1) is a truncated form of IGF-1 missing the first three N-terminal amino acids. This modification eliminates binding to IGFBPs entirely, making it approximately 10x more potent than native IGF-1 at the receptor level.
Ultra-Fast Acting
Due to zero IGFBP binding, IGF-DES has immediate and complete bioavailability upon administration. It acts rapidly on IGF-1 receptors but has a short half-life (~20-30 minutes), making it ideal for studying acute IGF-1 receptor activation.
Localised Research Applications
IGF-DES's short half-life and high potency make it particularly suited for localised tissue research, where rapid, intense IGF-1 receptor activation is desired in specific areas rather than systemic exposure.
Muscle Cell Proliferation Research
Research demonstrates IGF-DES potently stimulates myoblast proliferation and satellite cell activation. Its high receptor binding affinity and rapid action make it a powerful tool for studying muscle cell biology and hypertrophy pathways.
Cell Culture Applications
IGF-DES is used in cell culture to stimulate growth when complete, unbound IGF-1 activity is required. Its lack of IGFBP binding provides more predictable and immediate growth factor signalling in controlled research environments.
IGF System Pharmacology Tool
Comparing IGF-DES (zero IGFBP binding), IGF-1 LR3 (reduced binding), and native IGF-1 (normal binding) allows researchers to precisely study the role of IGFBPs in modulating IGF-1 signalling — a key area of growth factor biology.
Note: The health benefits listed above are based on published scientific research and clinical studies. Individual results may vary. This product is sold for research purposes only — not for human consumption. Always consult published literature for detailed study methodologies and findings.
Frequently Asked Questions — IGF-DES 2mg
What is IGF-DES?
IGF-DES (Des(1-3) IGF-1) is a truncated analogue of insulin-like growth factor 1, missing the first three amino acids (Gly-Pro-Glu) from the N-terminus. This naturally occurring variant does not bind to any of the six IGF-binding proteins, making it approximately 10x more potent than native IGF-1 but with a much shorter half-life (~20-30 minutes).
How does IGF-DES compare to IGF-1 LR3?
IGF-DES is more potent (~10x native IGF-1) but shorter-acting (20-30 minute half-life) compared to IGF-1 LR3 (~2-3x native IGF-1, 20-30 hour half-life). IGF-DES has zero IGFBP binding while LR3 has greatly reduced but not eliminated binding. Researchers choose between them based on whether they need intense, acute activation (DES) or sustained, systemic activity (LR3).
Why does removing three amino acids increase potency?
The N-terminal tripeptide (Gly-Pro-Glu) of native IGF-1 is critical for IGFBP binding. Removing it eliminates this binding entirely, meaning 100% of administered IGF-DES is immediately available to activate IGF-1 receptors. With native IGF-1, ~99% is bound to IGFBPs at any given time, leaving only ~1% free to signal.
Can I buy IGF-DES in Australia?
Yes — OzTideLab ships IGF-DES 2mg across Australia via Australia Post. Free standard shipping on orders over A$199. HPLC-verified ≥98% purity, discreet packaging, and PayID/Osko payment accepted.
Research Applications
This peptide is supplied for in-vitro laboratory research only. Common research applications include receptor binding assays, cell culture studies, structure-activity relationship analysis, and bioassay development. Researchers should consult relevant literature for specific experimental protocols.
Storage & Handling
- • Store lyophilised powder at -20°C for long-term stability
- • Short-term storage: 2-8°C (refrigerated)
- • Protect from light, moisture, and repeated freeze-thaw cycles
- • Once reconstituted, use within the recommended timeframe
Purity & HPLC Analysis
Every batch is independently verified via High-Performance Liquid Chromatography (HPLC) to confirm ≥98% purity. Mass spectrometry (MS) is used for molecular identity confirmation. Certificates of Analysis (CoA) are available on request — email support@oztidelab.com with your order number.
Reconstitution Guidelines
- • Use bacteriostatic water or sterile water for reconstitution
- • Add solvent slowly along the vial wall — do not shake
- • Gently swirl until fully dissolved (clear solution)
- • Store reconstituted solution at 2-8°C and use within 28 days
- • Use sterile technique throughout to prevent contamination
HPLC Verified
≥98% purity certified
Australian Owned
Local team, local support
Discreet Shipping
Plain packaging AU-wide
Research Grade
Lab-quality peptides
